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Independent audits of published clinical research for statistical errors, data inconsistencies, and research integrity violations.
Audit Clinical Evidence

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Peer review missed it.
We found it.

Audit Clinical Evidence protects the credibility of the scientific record. We audit published clinical research for errors and signs of falsification, fabrication, manipulation, and misconduct, then document it, publish it, and report it.

Browse the reports → How we audit
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ACE2026002 Artificially inflated effect size from a single RCT impacts 19 meta-analyses of exercise as a treatment for depression ✕ ACE2026001 One trial appears to be published as three separate RCTs of exercise for depression in heart failure ✕ ACE2026002 Artificially inflated effect size from a single RCT impacts 19 meta-analyses of exercise as a treatment for depression ✕ ACE2026001 One trial appears to be published as three separate RCTs of exercise for depression in heart failure ✕
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The record so far

What two audits found

Totals across every published report. They update with each new report and each new version.

ACE-RIV 139 Research integrity violations documented
Infected 514 Articles that cite the audited work
Infected 94 Systematic reviews built on it
Spread 26 Clinical guidelines it reached

Citation counts from OpenAlex, retrieved September 20, 2026. Integrity violations are counted under ACE-RIV.

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Latest audits

Published reports

Each report documents what can be verified from the public record, and shows how every finding was reached.

ACE2026002 10.5281/zenodo.23331178

Audit of Singh et al. (1997)

A randomized controlled trial of progressive resistance training in depressed elders

Older Adults Exercise Depression RCT
110 integrity violations Infected 440 articles 77 reviews 4 guidelines
Abstract
This report audits a randomized controlled trial by Singh, Clements, and Fiatarone that compared 10 weeks of progressive resistance training with an attention control condition in 32 community-dwelling adults aged 60 and over with major depression, minor depression, or dysthymia. Every table in the article labels the values reported in parentheses as standard deviations, yet the Methods state that they are standard errors. The article's test statistic values support the Methods (i.e., the parenthetical values are standard errors). The reported age ranges are impossible under the reported standard deviations. Additionally, the depression subgroup means in Table 4 are impossible under the whole-group standard deviations in Table 3. The largest post-test standardized mean difference that the article can support on any depression outcome is −0.72. We located 24 meta-analyses that report a study-level effect size for this trial. Of these, 19 meta-analyses assign @singh1997 a value larger than any possibly correct extraction of the effect size. The median assigned value is −2.74 and the largest is −5.04. Four report exactly −1.75, which is due to meta-analysts treating the parenthetical values of the BDI scores as standard deviations. One of these meta-analyses is a Cochrane review. Furthermore, five of the 10 categorical baseline p values can not be reproduced by any standard test of the reported contingency table cells. Later in the paper there is a reported subgroup mean that is impossible given its sample size. In total, this audit identifies 110 instances of Research Integrity Violations across two categories. Due to the pervasive contamination the misreporting has had on the evidence syntheses in this field, we recommend retraction.
PublishedOct 12, 2026
UpdatedOct 12, 2026
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Retraction recommended
ACE2026001 10.5281/zenodo.22780329

Audit of Abdelbasset et al. (2019)

Three randomized controlled trials on exercise and depression

Heart Disease Exercise Depression RCT
29 integrity violations Infected 74 articles 17 reviews 22 guidelines
Abstract
This report audits three randomized controlled trials by Abdelbasset and colleagues evaluating exercise interventions for depression in patients with congestive heart failure. The three articles appear to report overlapping arms from the same underlying clinical trial while presenting them as separate studies. Across the articles, duplicated baseline characteristics and PHQ-9 outcome statistics indicate reuse of the same trial data even though the articles report incompatible authorship contribution statements and three distinct ethical approval numbers, and do not cite one another. The articles are potentially linked to a well-documented authorship-for-sale publication network. Furthermore, one of the three articles identifies Abdelbasset as both first author and editor which is a clear conflict of interest. Reported summary statistics are impossible given a real data set, specifically, seven of nine PHQ-9 (the primary outcome) mean and standard deviation pairs fail GRIMMER consistency tests. The baseline tables report probability values that cannot be correct, including two different values for a single two-group comparison of a binary variable, while the continuous comparisons in the same tables reproduce exactly. The reported outcomes also imply extreme between-group standardized mean differences of approximately three standard deviations at post-intervention, making the studies highly influential outliers in later meta-analyses. In total, this audit identifies 29 instances of Research Integrity Violations across seven categories. We conclude that the three articles are not credible and are unlikely to contain any evidentiary value thus we recommend retraction by the publishing journals.
PublishedSep 13, 2026
UpdatedSep 20, 2026
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Retraction recommended
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How an audit works

Four steps

The same sequence for every report, from the first anomaly to a letter on the editor's desk.

  1. 01

    Find

    We identify errors in published articles via the tables, text, figures, trial registrations, supplements, and article metadata.

  2. 02

    Document

    Each finding and the relevant evidence is documented in the form of an audit report.

  3. 03

    Publish

    Reports are open access under CC BY 4.0, archived on Zenodo with a DOI, and versioned whenever they change.

  4. 04

    Report

    We send the report to the journal's editors and research integrity office, and follow the letter publicly until the journal makes a decision.

Every finding must be
  • Observable in the public record
  • Reproducible by an independent reader
  • Supported by the evidence
ACE-RIV v1.1

The ACE Taxonomy of Research Integrity Violations

Every finding in every report maps to a numbered category. Select one to see it. Badges count the instances documented so far.

1Authorship and Publication
2Statistical and Data Integrity
3Ethical Oversight and Transparency
4Indicators and Minor Issues
RIV 2.4Data Miscalculation or Erroneous Reporting86 instances documented so far
Documented in a published reportNot yet documentedRead the taxonomy →
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Found something in a published article?

Write us an email containing the article and the specific problem. Priority goes to concerns that are specific, tractable, reproducible, and relevant to clinical research. What to include.

Email contact@auditclinicalevidence.org

© 2026 Matthew B. Jané · Audit Clinical Evidence™

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Reports CC BY 4.0 · Code MIT